Harvard stem cell scientists have discovered that the clump of cells that gives rise to the embryonic heart also contains cells that form the heart’s plumbing, such as the aorta and the other great vessels.
While the discovery was made serendipitously by researchers working to illuminate the location of stem
Harvard Stem Cell researchers and collaborators have shown that they can grow unlimited quantities of intestinal stem cells, then stimulate them to develop into nearly pure populations of different types of mature intestinal cells. Using these cells,
Harvard Stem Cell Scientists have discovered that the same chemicals that stimulate muscle development in zebrafish can also be used to differentiate human stem cells into muscle cells in the laboratory, an historically challenging task that, now overcome, makes muscle cell therapy a more realistic clinical possibility.
Young animals are known to repair their tissues effortlessly, but can this capacity be recaptured in adults? A new study from Harvard Stem Cell Institute(HSCI) researchers at Boston Children’s Hospital suggests that it can. By reactivating a dormant gene called Lin28a, which is active in embryonic stem cells, researchers were able to regrow hair and repair cartilage, bone, skin
Harvard Stem Cell Institute (HSCI) Co-director Douglas Melton, PhD, and Evotec AG have entered into their second research collaboration to find biological pathways and signals that could be therapeutically relevant to diabetic patients.
The objective of this new collaboration, dubbed “TargetEEM” (Target Enteroendocrine Mechanisms), is to screen disease-relevant animal models for novel pathways and targets that have the potential to repair mechanisms involved in insulin resistance and abnormal