Harvard Stem Cell Institute (HSCI)

Our mission is to find cures for human diseases.

HSCI Mission

Harvard Stem Cell Institute (HSCI) scientists are working together across Harvard schools, centers, and teaching hospitals, harnessing the power of stem cells to change medicine for the better.

A lab scientist evaluates a red liquid substance in a container

Research

HSCI bridges the gaps in traditional research funding to encourage bold thinking and launch scientific careers.

Through our disease programs, we channel world-class resources, both intellectual and technological, toward some of the most prevalent, devastating diseases for which stem cell research holds promise.

In addition, our seed grants and junior faculty programs provide funding for innovative, early-stage projects in stem cell research. This allows up-and-coming scientists to pursue "high risk/high reward" avenues of research that might be difficult to fund from other sources.

Melanocyte stem cells affected by overstimulation of the parasympathetic nerve

How does stress affect stem cells? Here, we see elaborate sympathetic innervation (magenta) around melanocyte stem cells (yellow). Acute stress has triggered the release of large amounts of norepinephrine, depleting the melanocyte stem cells and causing hair to lose color. Image courtesy of Hsu Laboratory, Harvard University

Lee Rubin appointed faculty co-director of Harvard Stem Cell Institute

Lee Rubin, professor of stem cell and regenerative biology and leading scholar of neurodegenerative disease, has been named the next faculty co-director of the Harvard Stem Cell Institute (HSCI). Effective this spring, he joins current co-director David Scadden, Gerald and Darlene Jordan Professor of Medicine and professor of stem cell and regenerative biology, in leadership of the initiative.

Professor Lee Rubin in his Sherman Fairchild Lab

HSCI Faculty

HSCI has been breaking down barriers to collaboration in stem cell science since 2004. We provide fertile ground for more than 350 research faculty and their labs, across the university’s schools, centers, teaching hospitals, and partner companies, to share knowledge and pursue bold new ideas.

With Harvard as a wellspring of discovery and a strong network that embraces new ways of working, we are better equipped than ever to change human health in ways that will benefit all of society.

From Lab to Clinic

A key part of our mission is to move research out of the lab and into the clinic. Since our founding, we have been forging a clear path to translating discoveries into products that benefit patients. Now, we have the flexibility to organize people across institutions and sectors to tackle specific biological problems so we can make a lasting difference in people's lives.

researchers in lab

Stem-cell research news delivered straight to your inbox.

Sign up for the HSCI newsletter

Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center logo

Boston Children's Hospital

Boston Children's Hospital logo

Brigham and Woman's Hospital

Brigham and Women's Hospital logo

Dana-Farber Cancer Institute

Dana Farber Cancer Institute logo

Joslin Diabetes

bigger_joslinheader-redux2_0-1.png

McLean Hospital

McLean Hospital logo

Massachusetts Eye and Ear

Massachusetts Eye and Ear logo

Massachusetts General Hospital

Massachusetts General Hospital logo