Blood Diseases

Cell therapy for all

November 1, 2018

Chad Cowan is on a quest for the universal donor, which would make cell therapy available to populations – not just individuals.

  • Harvard scientist Chad Cowan aims to make off-the-shelf cellular products, and democratize access to new medicines.
  • His lab is working to make cellular therapies that can work for anyone, not just a single patient. 
  • Their ambitious goal is to modify therapeutic cells that can be transplanted into many people, without being rejected.

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One good drug

November 1, 2018

HSCI physician-scientists Daniel Tenen and Li Chai want to turn off a gene to stop cancer without poisoning the patient.

  • The ideal cancer drug would harm cancer cells without hurting normal cells.
  • In their quest to discover one good therapy, HSCI scientists Dan Tenen and Li Chai have zeroed in on SALL4, a gene that is essential for growth in both embryos and cancers.
  • A cellular therapy that deprives cancer cells of SALL4 would stop a third of cancers in their tracks.

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