Researchers at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS), in collaboration with Harvard Stem Cell Institute (HSCI), have discovered a new way in which the development of lung cancer can be stopped. In a study published in Science Translational Medicine, the researchers found that inhibiting a protein called BMI1 impaired tumour growth in lung cancer.
HSCI researchers sampled biopsies from women participating in the Nurses' Health Study. In healthy breast tissue (pictured above), the percentage of cells expressing molecular marker Ki67 (green) and p27 (red) Read more about New weapon against breast cancer
Mouse rhabdomyosarcoma tumors produced by activated muscle stem cells with high Yap activity (green; top panels) decrease in size when Yap activity is lowered (bottom panels, as shown by the green tumor cells starting to form muscle tissue and express normal muscle differentiation Read more about Molecule that drives rare childhood cancer discovered