In a cross-school collaboration, Harvard researchers Steve McCarroll (left) and Kevin Eggan (right) couple stem cell science with genetics and genomics to advance our understanding of human brain illnesses. Their latest project identified mutations that stem cell lines acquire in culture.
This scanning electron microscope image shows the T cell-trapping biomaterial up-close with cavities and ducts allowing the entry, as well as movement and binding of autoimmune T cells in its interior. Photo courtesy of James Weaver.
Bone marrow from a young boy diagnosed with Diamond-Blackfan anemia (DBA) shows a reduced number of erythroid precursor cells. In this case, an unusual gene mutation in the hormone EPO was identified and found to cause the anemia. Photo courtesy of Ekrem Unal.