SMN protein (red) is necessary for the survival of spinal cord neurons (motor neurons) responsible for breathing and all movement. Harvard researchers have found a compound that stabilized this protein in mouse and human motor neurons. This may lead to the development of new treatments for
President Drew Faust accepts the ALS Ice Bucket Challenge and is doused by Harvard’s ALS research team, led by Harvard Stem Cell Institute Principal Faculty member Kevin Eggan, PhD. She nominates MIT president Rafael Reif, UMass Boston Chancellor Keith Motley, and The Harvard Dorm Crew.
Using a new, stem cell-based, drug-screening technology that could reinvent and greatly reduce the cost of developing pharmaceuticals, researchers at the Harvard Stem Cell Institute (HSCI) have found a compound that is more effective in protecting the neurons killed in amyotrophic lateral sclerosis (ALS) than are two drugs that failed in human clinical trials after large sums were invested in them. Read more about New use for stem cells identifies a promising way to target ALS