HSCI researchers show the healing mechanisms of extracellular vesicles using a heart-on-a-chip

Researchers in the Jennifer Lewis lab have developed low...

Face masks and hand sanitizers are essential tools to prevent the spread of COVID-19. But what if these essentials could be supercharged? HSCI researchers are developing bioengineered protective materials, including a nasal spray that could keep the virus from entering the rest of the body, and a new...

Cancer immunologists and biological engineers at Harvard unite to fight therapy-resistant cancers

A new NIH-funded Immuno-Engineering to Improve Immunotherapy (i3) Center at Harvard University sets out to...

Biomaterial-based vaccine protects against acute myeloid leukemia in mice

HSCI scientists have combined organ-on-a-chip and stem-cell technologies to make a powerful tool for diabetes research and beta-cell transplantation

New microgel encapsulation method paves the way for more efficient cell therapies

Injectable, sponge-like gel helps revive the immune system after a bone marrow transplant

Method for growing kidney organoids under flow enhances their vascularization and maturation, increasing their potential for drug testing and regenerative medicine

George Murphy wants to use stem cells to replace scarring with regenerative healing.

• George Murphy’s goal is to coax skin stem cells into healing wounds by regenerating tissue instead of forming a scar.
• To figure out how to do it, he is studying scarless healing during fetal development and “stem cell burnout” during aging.
• Insights into scarless healing will help research into regenerating other vital organs, including the heart.

...

HSCI bioengineer and cardiologist collaborate to design a radically improved model of the heart

Advances in engineering blood cells, treating diabetes, regenerating joints, and growing organs

On May 31, 2018, Harvard Stem Cell Institute (HSCI) faculty members shared their research updates at the Harvard Medical School (HMS) Alumni Reunion symposium. Their work showcased the breadth of research being conducted across the HSCI network, both at Harvard University and its...

HSCI, a network of the nation’s top stem cell and regenerative medicine researchers, gathers to exchange ideas and forge new collaborations to advance biomedical research.

...

Press release of the Massachusetts General Hospital

Using human induced pluripotent stem cells (iPSCs), a Massachusetts General Hospital (MGH) research team has bioengineered functional small intestine segments that, when implanted into rats, were capable of deliver nutrients into the bloodstream. The investigators describe their accomplishment in the online journal Nature Communications.

“In this study we have been able to bridge the gap between differentiation of single cells – driving stem cells to become a specific cell type – and the...