We are interested in unlocking new paradigms of normal blood development with the long-term aim of building better models of childhood blood diseases.  The process of blood formation changes over a lifetime: the blood stem cells formed in the embryo, newborn, child, and adult differ in their self-renewal and output of mature cells.  We aim to understand the molecular regulation of how blood formation is ‘timed’ during development and aging and apply this knowledge to blood diseases, many of which are biased toward specific ages.

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Grant is an attending physician at Boston Children’s Hospital and the Dana-Farber Cancer Institute and Assistant Professor of Pediatrics at Harvard Medical School.  He completed his MD/PhD training at the University of Michigan, and his residency and fellowship training at Boston Children’s Hospital.