The Domian Laboratory is focused on adapting findings of basic developmental and stem cell biology to translational cardiovascular medicine.... Read more about Ibrahim Domian, MD, PhD
Massachusetts General Hospital Harvard Medical School
The Pediatric Surgical Research Laboratories focus on Developmental Biology, some areas of which hold promise for clinical application to benefit both pediatric and adult patients.... Read more about Patricia K. Donahoe, MD
Massachusetts General Hospital Harvard Medical School
We study kidney organogenesis using the zebrafish to explore conserved molecular mechanisms underlying kidney cell specification, differentiation, and organ patterning. We also study organ pathologies that results from mutations in genes required for cilia biogenesis and function. These include kidney cystic disease, retinal degeneration and left-right asymmetry defects.... Read more about Iain A. Drummond, PhD
Massachusetts General Hospital Harvard Medical School
Research in our laboratory is committed to expanding our molecular understanding of the formation and regeneration of tendons and ligaments. Injuries to...
Massachusetts General Hospital Harvard Medical School
My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through in vitro and modeling studies, with the ultimate goal of improving diagnosis, management and treatment.... Read more about James Gusella, PhD
Massachusetts General Hospital Harvard Department of Stem Cell and Regenerative Biology Howard Hughes Medical Institute
Our lab tries to understand the role that stem cells play in normal development and disease. Stem cells have the dual potential to self-renew and give rise...
Our laboratory is interested in the transcriptional regulation of normal blood cell development and leukemia. All blood cells arise from a small population...
Massachusetts General Hospital Harvard Medical School
The Hoggatt Laboratory is broadly interested in the stem cell niche regulatory mechanisms that govern tissue regeneration, particularly regulation by...
My laboratory studies how atherosclerosis—narrowing and hardening of the arteries—occurs. Atherosclerosis leads to abnormalities in blood vessels and...
Massachusetts General Hospital Harvard Medical School
Our research focuses on using the zebrafish to better understand human cancer and to develop novel insights into how it is that tumors can be remade following conventional chemotherapeutic intervention. Uncovering the downstream molecular pathways that lead to relapse will be integral to identifying novel drugs for the treatment of cancer.... Read more about David M. Langenau, PhD
Our research is focused on understanding the cell-type-specific responses to TGF-beta signaling in development and disease. TGF-beta signaling regulates...
Massachusetts General Hospital Harvard Medical School
Dr. Harald C. Ott is a fellow in cardiothoracic surgery at the Massachusetts General Hospital and an Instructor in Surgery at the Harvard Medical School. He...
Massachusetts General Hospital Harvard Medical School
The lung is a vertebrate invention that allowed the early tetrapods to leave the water and colonize the land. Oxygen is the essential actor in aerobic metabolism and the lung's cardinal function is to mediate the efficient transfer of oxygen from the atmosphere to the circulatory system. Given the lung's essential function, diseases of the lung are often life-threatening or incapacitating.... Read more about Jayaraj Rajagopal, MD
