Clifford Woolf wants to reboot drug discovery to find a new way to treat pain: effectively and responsibly.
Woolf’s goal is to stop the opioid crisis by rejecting the conventional approach to drug discovery and developing painkillers that do not harm people or communities.
He is using stem cells to create models of pain, outside the body and in a dish, that can be used to screen for drugs swiftly and on a large scale.
The new approach requires ‘all hands’: expertise, equipment, and collaboration in stem...
Co-lead of HSCI's Nervous System Diseases Program Paola Arlotta and postdoctoral fellow Giorgia Quadrato have produced long-cultured brain organoids that have the potential to advance our understanding of brain development and...