Discovery opens doors to improving diagnostics and developing new therapy for majority of ALS patients
Summary
HSCI-funded research using human pluripotent stem cell models and tissue from ALS patients found that the protein TDP-43 regulates a gene called Stathmin2 (STMN2).
Clifford Woolf wants to reboot drug discovery to find a new way to treat pain: effectively and responsibly.
Woolf’s goal is to stop the opioid crisis by rejecting the conventional approach to drug discovery and developing painkillers that do not harm people or communities.
He is using stem cells to create models of pain, outside the body and in a dish, that can be used to screen for drugs swiftly and on a large scale.
The new approach requires ‘all hands’: expertise, equipment, and collaboration in stem...
