Research Update

How insulin-producing cells show their age

April 6, 2017

Adapted from a Joslin Diabetes Center press release

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets. Using newly identified cellular markers of aging, Joslin Diabetes Center scientists now have shown that this diversity may be driven at least in part by differently aged beta cell populations within the pancreas. 

Additionally, the Joslin team demonstrated that the aging of beta cells, with associated losses of their… Read more about How insulin-producing cells show their age

Helping beta cells divide

March 17, 2017

 

Scientists identify a key barrier to proliferation of inuslin-producing cells

If you become resistant to insulin, a condition that is a precursor to type 2 diabetes, your body tries to compensate by producing more of the “beta” cells in the pancreas that produce the critical hormone. Researchers have long sought to understand why these cells often fail to proliferate in people who go on to develop the disease. Studying both humans and mice, scientists at Joslin Diabetes Center now have pinpointed one key biological mechanism that can prevent the… Read more about Helping beta cells divide