The JDRF Center of Excellence in New England will accelerate beta cell replacement therapy

Harvard Stem Cell Institute (HSCI) co-director Douglas Melton, Ph.D., will lead a new multi-institutional center funded by JDRF to advance type 1 diabetes research. The JDRF Center of Excellence in New England will focus on the transplantation of beta cells, the insulin-producing cells of the pancreas that are attacked by the immune system during type 1 diabetes.

The center is also led by JDRF scientific staff leader Esther Latres, Ph.D. Other collaborators include...

HSCI researchers create ON-OFF switches to better control CAR T cell activity

HSCI scientists have created molecular ON-OFF switches to regulate the activity of CAR T cells, a potent form of cell-based immunotherapy that has shown dramatic success in treating some advanced cancers, but...

Researchers identify a new level of complexity in how the brain responds to stimuli

HSCI scientists find that signaling defects can influence red blood cell traits

The field of genetics has made huge strides over the past couple of decades, from the first sequencing of the human genome to a growing understanding of the machinery that turns genes on and off — proteins called...