Principal Faculty

April M. Craft, PhD

April M. Craft, PhD

Assistant Professor, Boston Children's Hospital

Craft Lab research
Our research focuses on both developmental biology and translational medicine, and involves the use of pluripotent stem cells to understand how musculoskeletal lineages, primarily articular chondrocytes and cartilage tissues, are specified during embryonic development and how mature cells and... Read more about April M. Craft, PhD

George Q. Daley head shot

George Q. Daley, MD, PhD

Dean, Faculty of Medicine, Harvard Medical School
Boston Children's Hospital
Howard Hughes Medical Institute

George Q. Daley, M.D., Ph.D, seeks to translate insights in stem cell biology into improved therapies for genetic and malignant diseases. Important research contributions from his laboratory include the creation of customized stem cells to treat genetic immune deficiency in a mouse model (together with Rudolf Jaenisch), the differentiation of germ cells from embryonic stem cells (cited as a “Top Ten Breakthrough” by Science magazine in 2003), and the generation of disease-specific pluripotent stem cells by direct reprogramming of human fibroblasts (cited in the “Breakthrough of the Year” issue of Science magazine in 2008).... Read more about George Q. Daley, MD, PhD

Iain A. Drummond, Ph.D.

Iain A. Drummond, Ph.D.

Associate Professor, Medicine, Harvard Medical School
Associate Biologist, Renal Unit, Massachusetts General Hospital

We study kidney organogenesis using the zebrafish to explore conserved molecular mechanisms underlying kidney cell specification, differentiation, and organ patterning. We also study organ pathologies that results from mutations in genes required for cilia biogenesis and function. These include kidney cystic disease, retinal degeneration and left-right asymmetry defects.... Read more about Iain A. Drummond, Ph.D.

Ben Ebert headshot

Benjamin L. Ebert, MD, PhD

Brigham and Women's Hospital
Dana-Farber Cancer Institute
Harvard Medical School | Broad Institute

The Ebert laboratory focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS). In large-scale genetic analyses of patient samples, the lab has identified somatic mutations that predict prognosis and response to therapies in MDS patients. The also focuses on a pre-... Read more about Benjamin L. Ebert, MD, PhD

Yick W. Fong, PhD

Yick W. Fong, PhD

Brigham and Women's Hospital
Harvard Medical School

Transcriptional mechanisms of pluripotency and cellular reprogramming

We study key transcriptional and gene regulatory events that lead to the acquisition and maintenance of pluripotency in embryonic stem cells (ESCs).  ESCs can self-renew or differentiate to produce most of the cells of the body. These distinct but developmentally relevant cell fates are defined by their unique gene expression signatures. Proper execution of these developmental programs requires the precise tuning of gene expression by transcription factors, coactivators and corepressors.  Indeed, aberrant transcriptional regulation is the root of many human diseases including developmental disorders, cancers and degenerative diseases.... Read more about Yick W. Fong, PhD

Markus Frank, MD

Markus Frank, MD

Associate Professor of Pediatrics and Dermatology, Harvard Medical School

Markus Frank’s laboratory research focuses on the physiological and pathological roles of the P-glycoprotein family of ATP-binding cassette (ABC) multidrug...

Read more about Markus Frank, MD
Boston Children's Hospital
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