Paola Arlotta

Neurons reprogrammed in animals

November 4, 2015

Building on earlier work in which they disproved neurobiology dogma by “reprogramming” neurons — turning one form of neuron into another — in the brains of living animals, Harvard Stem Cell Institute researchers have now shown that the networks of communication among reprogrammed neurons and their neighbors can also be changed, or “rewired.”

The finding, by Paola Arlotta, a professor of...

Read more about Neurons reprogrammed in animals

Unique collaborative effort proves value of some “junk” genes

January 21, 2014

From his days in graduate school, through his postdoctoral fellowship, and now as a Harvard Stem Cell scientist, John Rinn, PhD, has been digging through the bulk of the human genome, challenging the prevailing belief that the bulk of the genome is biological “junk.” Ever since the Human Genome Project decoded the genome, the prevailing view has been that only the two percent of the genome making proteins, the building blocks of cells, was important. The rest of the genome was deemed not functional, or “junk.”... Read more about Unique collaborative effort proves value of some “junk” genes

Doing the neuron tango

February 23, 2011

To an untrained observer, the electrical storm that takes place over the brain’s neural network seems a chaotic flurry of activity. But as neuroscientists understand it, the millions of neurons are actually engaged in a sort of tightly choreographed dance, a tango of excitatory and inhibitory neurons. How is this precise balance...

Read more about Doing the neuron tango