Blood Diseases Program

Mitochondrial DNA sequencing reveals the true origins of cells

April 9, 2019

There are many more cell types than you might think. In your liver, for example, the cells in one section may be different than those in another. But researchers have only a general idea of how stem cells differentiate into broad categories (like “liver”) and divide to make new cells.

Understanding each different cell type – and how it interacts with its neighbors over time – is one of the greatest challenges in biomedical research.

A new study led by HSCI researcher Vijay...

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One good drug

November 1, 2018

HSCI physician-scientists Daniel Tenen and Li Chai want to turn off a gene to stop cancer without poisoning the patient.

  • The ideal cancer drug would harm cancer cells without hurting normal cells.
  • In their quest to discover one good therapy, HSCI scientists Dan Tenen and Li Chai have zeroed in on SALL4, a gene that is essential for growth in both embryos and cancers.
  • A cellular therapy that deprives cancer cells of SALL4 would stop a third of cancers in their tracks.

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Call for Proposals: 2017-2018 HSCI Blood Program Pilot Grants

October 20, 2017

The Harvard Stem Cell Institute (HSCI) Blood Program invites applications for its 2017-2018 Pilot Grant cycle. The purpose of this funding program is to provide resources for projects in the field of blood stem cell biology with a basic, translational, or clinical research focus. HSCI is seeking to fund groundbreaking, innovative, high-impact research projects that could fundamentally enhance biomedical research in the field. Of particular interest to HSCI at this time is research...

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