The Anc80 virus delivered genes to the mouse retina that fluoresce green when expressed. Pictured here,...

Compounds boost stem cell engraftment; could allow more matches for patients with cancer and blood diseases

Using large-scale zebrafish drug-screening models,...

Above, the CCR2- blood stem cell (green) is positioned closer to bone (blue) compared to the rare CCR2+ blood stem cells (white). Generally, cells closer to the bone are more likely...

Above, human brown fat progenitor cells express the calorie-burning, UCP1 proteins (green) as the cell differentiates. (Tseng Laboratory, Joslin Diabetes Center) 

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Experimental technique used to create whole organs appears feasible for creation of complex tissue

Above, a suspension of muscle progenitor cells is injected into the cell-free matrix of a decellularized rat limb, which provides shape and structure onto which...

Wednesday, 25 March 2015

HSCI Principal Faculty member Connie Cepko and postdoctoral researcher Wenjun Xiong talk about developing a gene therapy to stave off blindness. Video: Rick Groleau

Gene therapy slows vision loss in mouse models of retinal degeneration

By...

In the top image the frog embryo is developing normally. In the bottom image the frog embryo is lacking a head and brain as a result of the suppression of the Notum protein.

Researchers identify a vital protein that can determine head and brain development

By Hannah...

Ole Isacson and colleagues reported that dopamine-producing neurons (pictured) derived from the skin cells of primates survived for more than two years after implantation into one of the animals. Isacson noted that...

Mesenchymal stem cells (green) colonize a pancreatic islet in a preclinical model of diabetes. The blue dots represent the nuclei of cells within the islet.

by Haley Bridger, Brigham and Women's...

Above, one type of hypothalamic neuron created from stem cells. For the first time, researchers have access to these live human neuron types that are involved in everything from the regulation of sleep, to obesity, and...

Submission Deadline: 5 PM EST, Friday, March 6, 2015

The Harvard Stem Cell Institute (HSCI) invites applications for the 2015 cycle of Development Grants thanks to the Bowes Acceleration Fund. Development grants are different from the HSCI Seed Grants and Disease Program Pilot Grants. In line with the intent of this fund, this program will provide resources for innovative, high-impact projects that are ready to be “accelerated” into a development or translational phase or can be prepared for such a phase as a result of the proposed funding. Projects may be in any...

The HSCI Center for Stem Cell Bioinformatics helps HSCI researchers store, interpret, and integrate complex high dimensional stem cell data. It has supported over 400 projects across the Harvard community, many of which developed into funded collaborations. The consulting core can provide grant support and guidance on...