Scott Armstrong, MD, PhD

Scott Armstrong, MD, PhD

Dana-Farber Cancer Institute
Boston Children's Hospital
Harvard Medical School | Broad Institute of MIT and Harvard
Scott Armstrong MD PhD photo

The Armstrong laboratory is focused on the mechanisms of cancer development with a focus on leukemia. One major interest in the lab is the relationship between leukemia, normal hematopoietic stem cells and the various hematopoietic cells of origin of leukemia. The lab is also studying the role of histone modifications and chromosome structure as a critical initial step in cancer development and how these mechanisms can be targeted therapeutically. This work has prompted a search for therapies that can reverse this process and eradicate cancer cells, and has led to the development of new therapies that are now being tested in patients.

Dr. Armstrong is the Chairman of Pediatric Oncology at the Dana Farber Cancer Institute and Associate Chief of the Division of Hematology and Oncology at Boston Children’s Hospital. He was previously the Director of the Center for Epigenetics Research at Memorial Sloan Kettering Cancer Center and Professor of Pediatrics at the Weill Cornell Medical College where he initiated a research program in cancer epigenetics that has made significant contributions to the understanding of cancer biology. The major focus of his career has been on delineating the biology of childhood cancers, particularly leukemia. His work has led to the development of new therapeutic approaches for multiple types of cancer that are now being tested. Dr. Armstrong received his MD and PhD from the University of Texas Southwestern Medical School in Dallas, Texas. He performed his residency and fellowship in pediatric hematology/oncology at Children’s Hospital Boston, the Dana Farber Cancer Institute, and Harvard Medical School. Dr. Armstrong's work has been recognized by multiple awards including the Till and McCulloch Award from the International Society of Experimental Hematology, the Paul Marks Prize for Cancer Research from Memorial Sloan Kettering Cancer Center, the E. Mead Johnson Award from the Society for Pediatric Research, and the Dameshek Prize from the American Society of Hematology. He is an elected member of the American Society of Clinical Investigation (ASCI), the Association of American Physicians (AAP), and is a fellow of the Association for the Advancement of Science.

Link to Pubmed articles by Scott Armstrong, MD, PhD

News links:

Scott Armstrong MD, PhD to lead DFCI Department of Pediatric Oncology

New therapeutic approach shows promise in patients.

Scott Armstrong MD, PhD awarded Dameshek prize from the American Society of Hematology