Harvard Medical School

Clifford Woolf aims to reboot drug discovery to find a new way to treat pain and neurodegenerative diseases: effectively and responsibly.

Research in the Woolf group is devoted to investigating the way in which the functional, chemical and structural...

An internationally renowned researcher, Dr. Williams' work focuses on blood stem cell biology, leukemia, and gene therapy to correct genetic blood disorders.

The Williams lab investigates the biology of hematopoietic stem cells, focusing on analysis of the...

Dr. Gordon Weir has combined a career of caring for patients with diabetes with an intensive research focus on beta-cell replacement therapy.

One of the most important goals of diabetes research is to find sources of new beta cells (the islet cells in...

The Walsh lab studies the development of the human cerebral cortex, from undifferentiated stem cells to mature neurons. Studies of families with genetic disorders of human brain development have allowed us to identify of dozens of genes essential for...

The Tseng laboratory investigates the mechanisms underlying the regulation of energy balance to develop potential therapies for combating obesity and related diseases.

Obesity is an epidemic health problem worldwide, which results from an imbalance...

Research in Ramesh Shivdasani's laboratory focuses on gastrointestinal cells and cancer.

A major focus of the Shivdasani the laboratory is to understand molecular mechanisms of gut development, in particular the transcriptional control of epithelial...

The Shah lab seeks to develop and test novel, targeted, cell-based therapies for brain cancers.

Successful treatment of brain tumors remains one of the greatest challenges in oncology. The recognition that different cell types that have therapeutic...

The incidence and complexity of mental illnesses and cognitive impairments associated with aging and Alzheimer’s disease underscores the need to develop novel treatments. Our mission is to generate fundamental insights into the role of hippocampal...

The Ritz lab seeks to distinguish graft-versus-leukemia (GVL) response from graft-versus-host disease (GVHD) and to develop new methods for selectively enhancing GVL.

Allogeneic hematopoietic stem cell transplantation (HSCT) is widely used in the treatment...

The Rajagopal lab focuses on organ regeneration and the application of developmental biology to human disease. They utilize the lung as a model system, in part due to the abundance of respiratory diseases of unknown causes and without cures.

The lung is...