Harvard Medical School

Scott Armstrong MD PhD photo

Scott Armstrong, MD, PhD

Dana-Farber Cancer Institute
Boston Children's Hospital
Harvard Medical School | Broad Institute of MIT and Harvard

The Armstrong laboratory is focused on the mechanisms of cancer development with a focus on leukemia. One major interest in the lab is the relationship between leukemia, normal hematopoietic stem cells and the various hematopoietic cells of origin of leukemia. The lab is also studying the role of histone modifications and chromosome Read more about Scott Armstrong, MD, PhD

Elliot Chaikof, MD, PhD

Elliot Chaikof, MD, PhD

Beth Israel Deaconess Medical Center
Harvard Medical School
Wyss Institute for Biologically Inspired Engineering

Elliot L. Chaikof, MD, PhD, has promoted alliances of clinicians, engineers, chemists, and biologists and in the process developed biologically-inspired materials, devices, and pharmacotherapeutics based upon the principles of molecular engineering and nanofabrication technologies. These endeavors have enabled advances in cell-based therapies, artificial organs, and engineered living tissues, which define the evolving field of Regenerative Medicine. … Read more about Elliot Chaikof, MD, PhD

April M. Craft, PhD

April M. Craft, PhD

Assistant Professor, Boston Children's Hospital

Craft Lab research
Our research focuses on both developmental biology and translational medicine, and involves the use of pluripotent stem cells to understand how musculoskeletal lineages, primarily articular chondrocytes and cartilage tissues, are specified during embryonic development and how mature cells and … Read more about April M. Craft, PhD

George Q. Daley, MD, PhD

George Q. Daley, MD, PhD

Dean, Faculty of Medicine, Harvard Medical School
Boston Children's Hospital
Howard Hughes Medical Institute

George Q. Daley, M.D., Ph.D, seeks to translate insights in stem cell biology into improved therapies for genetic and malignant diseases. Important research contributions from his laboratory include the creation of customized stem cells to treat genetic immune deficiency in a mouse model (together with Rudolf Jaenisch), the differentiation of germ cells from embryonic stem cells (cited as a “Top Ten Breakthrough” by Science magazine in 2003), and the generation of disease-specific pluripotent stem cells by direct reprogramming of human fibroblasts (cited in the “Breakthrough of the Year” issue of Science magazine in 2008).  … Read more about George Q. Daley, MD, PhD

Iain A. Drummond, PhD

Iain A. Drummond, PhD

Massachusetts General Hospital
Harvard Medical School

We study kidney organogenesis using the zebrafish to explore conserved molecular mechanisms underlying kidney cell specification, differentiation, and organ patterning. We also study organ pathologies that results from mutations in genes required for cilia biogenesis and function. These include kidney cystic disease, retinal degeneration and left-right asymmetry defects.… Read more about Iain A. Drummond, PhD

Susan Dymecki, MD, PhD

Susan Dymecki, MD, PhD

Harvard Medical School

The step-by-step differentiation of embryonic cells into different types of neurons lays the foundation for our sensory responses, motor commands, and cognitive behaviors. Our research explores such differentiation programs in mammals using a combination of genetic, embryological, and molecular biological methods. While the generation of such neural diversity is a complex process culminating in the most sophisticated of wiring circuits, one simplifying approach is to start by tracking the specification, differentiation, and migration paths taken by specific sets of cells originating from primitive neuroectoderm. … Read more about Susan Dymecki, MD, PhD

Benjamin Ebert, MD, PhD

Benjamin Ebert, MD, PhD

Brigham and Women's Hospital
Harvard Medical School

The primary focus of the Ebert laboratory is the biology and treatment of clonal hematopoiesis and myeloid malignancies. Our genetic studies have led to the characterization of clonal hematopoiesis of indeterminate potential (CHIP) and the identification of mutations in MDS that predict overall survival, outcome following bone marrow transplantation, … Read more about Benjamin Ebert, MD, PhD

Yick W. Fong, PhD

Yick W. Fong, PhD

Brigham and Women's Hospital
Harvard Medical School

Transcriptional mechanisms of pluripotency and cellular reprogramming

We study key transcriptional and gene regulatory events that lead to the acquisition and maintenance of pluripotency in embryonic stem cells (ESCs).  ESCs can self-renew or differentiate to produce most of the cells of the body. These distinct but developmentally relevant cell fates are defined by their unique gene expression signatures. Proper execution of these developmental programs requires the precise tuning of gene expression by transcription factors, coactivators and corepressors.  Indeed, aberrant transcriptional regulation is the root of many human diseases including developmental disorders, cancers and degenerative diseases. … Read more about Yick W. Fong, PhD

Markus Frank, MD

Markus Frank, MD

Associate Professor of Pediatrics and Dermatology, Harvard Medical School

Markus Frank’s laboratory research focuses on the physiological and pathological roles of the P-glycoprotein family of ATP-binding cassette (ABC) multidrug… Read more about Markus Frank, MD

Boston Children's Hospital
Enders Research Building, Room 507
300 Longwood Avenue
Boston, MA 02115
p: 617-919-2993

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