Date:
Location:
Lecturers:
- Dr. Chad Nusbaum, Co-director, Genome Sequencing and Analysis Program, Broad Institute
- Dr. Peter Park, Associate Professor of Pediatrics, Children’s Hospital, and HMS Center for Biomedical Informatics
- Mr. Robert Steen, Director, Harvard Medical School Biopolymers Facility
Description:
Traditional capillary sequencing technology using base-specific chain termination by fluorescent di-deoxy nucleotides represents modifications to the original sequencing methodology devised by Sanger and colleagues in the 1970s. Recent years have seen the development of next generation parallel sequencing technologies that are rapidly replacing older methodologies. Sequencing by synthesis enables the simultaneous sequence analysis of millions of DNA templates at the same time, or in parallel. These new approaches allow for DNA sequencing at a markedly faster pace, and often at a much cheaper price, making sequencing projects feasible for an ever-expanding number of researchers. This nanocourse will explore the methodology and principles behind parallel sequencing technology, and how it measures up to traditional sequencing methods. A discussion of the services available at the Department of Genetics Biopolymers core facility, including order placement, data output, and turnaround times, will also be included for researchers interested in utilizing these resources.
For additional course and registration information, see https://nanosandothercourses.hms.harvard.edu/node/311
 | seqposter2014.pdf | 70 KB |