Scientists identify a key barrier to proliferation of inuslin-producing cells
If you become resistant to insulin, a condition that is a precursor to type 2 diabetes, your body tries to compensate by producing more of the “beta” cells in the pancreas that produce the critical hormone. Researchers have long sought to understand why these cells often fail to proliferate in people who go on to develop the disease. Studying both humans and mice, scientists at Joslin Diabetes Center now have pinpointed one key biological mechanism that can prevent...
Newly formed cochlear hair cells contain intricate hair bundles with many stereocilia (critical for sensing sound) and other components that are critical for proper function and neural transmission. Photo courtesy of Will McLean
HSCI researchers developed a drug cocktail that...
Dana-Farber Cancer Institute Boston Children's Hospital Harvard Medical School | Broad Institute of MIT and Harvard
Scott Armstrong studies the mechanisms of cancer development, focusing on leukemia. One major interest of this lab is the relationship between leukemia,...
Massachusetts General Hospital Harvard Medical School
We study human biology. Specifically, our current research is focused on the imaging and quantitative measurement of cancer biology and its treatment in vivo.... Read more about Ralph Weissleder, MD, PhD
Co-chair, Harvard Department of Stem Cell and Regenerative Biology Senior Investigator, Islet Cell and Regenerative Biology, Joslin Diabetes Center
Amy Wagers seeks to change the way we repair our tissues after an injury. Her research focuses on defining the factors and mechanisms that regulate the...
Massachusetts General Hospital Harvard Medical School
As a surgeon-scientist in the field of Pediatric Surgery and Transplantation Surgery, my major areas of investigation and interest began with two specific diseases that are highly lethal in children; namely congenital diaphragmatic hernia and congenital biliary atresia.... Read more about Joseph Vacanti, MD
Vice Chair of Research, Department of Neurosurgery, Brigham and Women's Hospital Director, Center for Stem Cell and Translational Immunotherapy, Brigham and Women's Hospital Professor, Harvard Medical School
The Shah lab seeks to develop and test novel, targeted, cell-based therapies for brain cancers.
Senior VP for Research and Development, Tesaro, Inc.
Metastatic cancers are the major reason for treatment failure in the clinic, but we lack a detailed understanding of how primary tumors metastasize, why these secondary tumors are relatively drug resistant, and what enables cancer cells to remain dormant and then cause disease relapse many years after apparently curative treatment. We are taking a multidisciplinary approach to attack these fundamental and related problems. Our major goal is to identify important cancer gene networks that are essential in human cancer progression, to guide the development and clinical use of new cancer drugs and diagnostics.... Read more about Sridhar Ramaswamy, MD
Our group is working on cancer genetics, using the zebrafish genetic system to clarify developmental pathways subverted in human leukemias and solid...
Harvard Department of Stem Cell and Regenerative Biology Brigham and Women's Hospital
Richard T. Lee's laboratory seeks to understand heart failure and metabolic diseases that accompany human aging, and to translate that understanding into...