Current and former HIP interns launch research projects on the same rocket

by Hannah L. Robbins

Mosquitos buzzed in the warm, night air at Cape Canaveral, Florida. Half past midnight on July 18, and still the spectators could not detect activity on the launch pad. In the dark, among fellow scientists and students, Harvard Stem Cell Institute Internship Program (HIP) intern Michael Liu waited.

Roughly two miles away, the SpaceX Falcon9 rocket stood on Space Launch Complex 40 ready to launch the Dragon spacecraft. Among two...

The Harvard Stem Cell Institute (HSCI), three of Harvard’s clinical affiliates, and a biopharmaceutical company have formed an unusual collaboration to establish the Boston Autologous Islet Replacement Program (BAIRT)...

Researchers at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS), in collaboration with Harvard Stem Cell Institute (HSCI), have discovered a new way in which the development of lung cancer can be stopped. In a study published in Science Translational Medicine, the researchers found that inhibiting a protein called BMI1 impaired tumour growth in lung cancer.

The study was led by HSCI Principal Faculty member Daniel Tenen, MD, his associate Elena Levantini, PhD, and included first author Dr Kol Jia Yong, a former CSI...

In the spleen, lymphoid tissue (purple) is responsible for launching an immune response to blood-born antigens, while red pulp (pink) filters the blood. Mutations in the C9ORF72 gene, the most common mutation found in ALS patients, can inflame...

Cambridge, MA, June 16,2016 - The Harvard Stem Cell Institute, three of Harvard’s clinical affiliates, and a biopharmaceutical company have formed a unique collaboration to establish the Boston Autologous Islet Replacement Program (BAIRT) to accelerate a cure for...

by Haley Bridger, Brigham and Women's Hospital 

A collaborative Harvard Stem Cell Institute (HSCI), Brigham and Women's Hospital (BWH) and Johns Hopkins University (JHU) co-led team has found proof-of-concept evidence for a potential cancer treatment that...

New study shows that circadian rhythm circuitry is essential for acute myeloid leukemia stem cells but not healthy blood cells, suggesting possible pathways for therapeutics

By Veronica Meade-Kelly, the Broad Institute of MIT and Harvard

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New approach offers promise for long-term efficacy

by Kelly Lawman, Beth Israel Deaconess Medical Center 

Blood-contacting implantable medical devices, such as stents, heart valves, ventricular assist devices, and extracorporeal support systems, as well as vascular grafts and access catheters, are used worldwide to improve patients’ lives. However, these devices are prone to failure due to the body’s responses at the blood-material interface; clots can form and inflammatory reactions can prevent the device from performing as indicated....

HSCI researchers sampled biopsies from women participating in the Nurses' Health Study. In healthy breast tissue (pictured above), the percentage of cells expressing molecular...

Young-Pearse and colleagues studied human astrocytes (red) and neurons (green) derived from iPS cells. Photo courtesy of Sarah Sullivan.

Study of plaque production holds promise for improved treatments...

Callosal projection neurons (green) in the cerebral cortex. Photo courtesy of Jessica MacDonald and Jeffrey Macklis. 

Researchers identify important signaling pathway, potential new route to therapy

by Hannah L. Robbins

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