The activity of four transcription factors—proteins that regulate the expression of other genes—appears to distinguish the small proportion of glioblastoma...
Harvard stem cell scientists have discovered that a recently approved medication for epilepsy may possibly be a meaningful treatment for amyotrophic lateral sclerosis (ALS)—Lou Gehrig’s disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital to design an initial clinical trial testing the safety of the treatment in ALS patients.... Read more about Patient stem cells help identify common problem in ALS
A Harvard Stem Cell Institute (HSCI) collaboration between a molecular chemist who studies microRNAs and a stem cell biologist interested in cell growth has led to new understanding of what goes wrong in several kinds of cancer.
Harvard stem cell scientists have made an unexpected and potentially useful discovery that the sound-sensing cells of the mammalian ear—called hair cells--can be replaced, at least at low levels. Despite years of evidence indicating that ear sensory cells do not regenerate if lost, new research from the laboratory of...
Harvard stem cell scientists studying the effect of nitric oxide on liver growth and regeneration appear to have serendipitously discovered a markedly improved treatment for liver damage caused by acetaminophen toxicity—the cause of half the U.S. hospital visits related to acute liver failure.
Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell’s fate, the researchers found, is determined by the nearby presence of prostaglandin E2, a messenger molecule best known for its role in...
Harvard stem cell researchers have shown that it may one day be possible to treat several lung diseases by introducing proteins that direct lung stem cells to grow the specific cell types needed to repair the lung injuries involved in the conditions.
Since the discovery of human embryonic stem cells, scientists have had high hopes for their use in treating a wider variety of diseases because they are pluripotent, which means they are capable of differentiating into one of many cell types in the body.
However, the acquisition of human embryonic stem cells from an embryo can cause the destruction...
The Harvard Stem Cell Institute (HSCI) invites applications for Pilot Grant funding for 2014 under the NIH-funded P01 grant “Dissecting the establishment and regulation of human pluripotency” (PI Alexander Meissner, Harvard Department of Stem Cell and Regenerative Biology). The purpose of this funding program is to provide resources for proof-of-concept studies. These pilot grants are intended to increase our...
The activity of four transcription factors—proteins that regulate the expression of other genes—appears to distinguish the small proportion of 
Harvard stem cell scientists at 
Harvard stem cell scientists have discovered that a recently approved medication for epilepsy may possibly be a meaningful treatment for 
Harvard stem cell scientists studying the effect of nitric oxide on liver growth and regeneration appear to have serendipitously discovered a markedly improved treatment for liver damage caused by acetaminophen toxicity—the cause of half the U.S. hospital visits related to acute liver failure.
Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell’s fate, the researchers found, is determined by the nearby presence of prostaglandin E2, a messenger molecule best known for its role in...
