Fat cells (yellow) descended from transplanted human mesenchymal stem cells (green) inside of a mouse 28 days after a co-transplantation procedure. The red stain shows mouse fat cells. The blue stain shows cell nuclei. (Credit: Juan Melero-Martin, PhD)
A new blood test has the potential to reveal whether a person recently diagnosed with type 1 diabetes is already at risk for kidney failure—information that might allow physicians to alter the course of treatment and slow disease progression.
This is the hope of Harvard Stem Cell Institute (HSCI) scientists at Brigham and Women’s Hospital who recently demonstrated that a laboratory test could detect, in the blood of mice and humans, the...
JDRF requests letters of intent for: Glucose responsive insulin discovery and validation
PURPOSE: JDRF, the world’s leading non-profit organization with the mission to cure, treat and prevent type 1 diabetes (T1D), invites Letters of Intent (LOI) for the discovery and validation of novel glucose responsive insulin (GRI) drugs for better treatment of insulin-dependent diabetes mellitus (IDDM) and reducing the burden of daily management of the disease, particularly T1D.
When the Hippo pathway is inactivated, mature liver cells revert back to a stem cell-like state. Picture shows a group of cells transitioning from a mature cell type (green) to a stem cell type (red). White cells are the cells where Hippo is...
Lee Rubin, PhD, and Amy Wagers, PhD, (below) of the Harvard Stem Cell Institute provide more evidence that a protein known as GDF11 reverses signs of aging in mice. (Credit: B.D. Colen/Harvard University)