Adding two small molecules to mouse iPS cell recipe grows colonies in 48 hours
Harvard Stem Cell Institute scientists at Massachusetts General Hospital have found that adding two small molecules to the four classic “Yamanaka factors” generates the...
Harvard/MIT team finds that killing cancer cells by disrupting their metabolism doesn’t harm normal cells
A study comparing how blood stem cells and leukemia cells consume nutrients found that cancer cells are far less tolerant to shifts in their energy supply than their...
President Drew Faust accepts the ALS Ice Bucket Challenge and is doused by Harvard’s ALS research team, led by Harvard Stem Cell Institute Principal Faculty member Kevin Eggan, PhD. She nominates MIT president Rafael Reif, UMass Boston Chancellor Keith Motley, and The Harvard Dorm Crew.
Researchers experiment with single shot that slows rejection
A drug-secreting gel that holds back the immune system—developed to help treat diseases such as brain cancer, ulcerative colitis, and arthritis—has now been shown to slow hand transplant rejection, in rats, when delivered through a single shot. The success may yield a new...
Mouse rhabdomyosarcoma tumors produced by activated muscle stem cells with high Yap activity (green; top panels) decrease in size when Yap activity is lowered (bottom panels, as shown by the green tumor cells starting to form muscle tissue and express normal muscle differentiation...
Harvard Stem Cell Institute scientists at the Joslin Diabetes Center have created induced pluripotent stem cells (iPSCs) that offer a human model of insulin resistance—a key driver of type 2...
