Cancer

HSCI scientist recognized for outstanding dermatology research

May 26, 2020

HSCI scientist Ya-Chieh Hsu, Ph.D. is the recipient of the 2020 LEO Foundation Award. The award recognizes extraordinary contributions to dermatology research that advance our understanding of skin diseases, and have the potential to pave the way for new and improved treatments.

Hsu is the Alvin and Esta Star Associate Professor of Stem Cell and Regenerative Biology. She studies how communication among different cell...

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Assassinating cancer

November 1, 2018

Mario Suva and Ramesh Shivdasani are tackling some of the toughest, meanest cancers to clear a path to better treatments.

  • Suva and Shivdasani are using every approach in their arsenal to figure out what makes cancer cells arise from healthy tissue.
  • Armed with enough new knowledge about how cancer arises, they want to take truer aim at cancer cells, the cancer cell lineage, and factors that make cells go awry.
  • Their new approach to cancer management would combine gene and cell therapies to kill the cancer...
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One good drug

November 1, 2018

HSCI physician-scientists Daniel Tenen and Li Chai want to turn off a gene to stop cancer without poisoning the patient.

  • The ideal cancer drug would harm cancer cells without hurting normal cells.
  • In their quest to discover one good therapy, HSCI scientists Dan Tenen and Li Chai have zeroed in on SALL4, a gene that is essential for growth in both embryos and cancers.
  • A cellular therapy that deprives cancer cells of SALL4 would stop a third of cancers in their tracks.

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