Acute myelogenous leukemia (AML) is one of the most common types of leukemia—a cancer of the bone marrow and blood—in adults, affecting about 13,300 women and men in the United States annually. The disease is also diagnosed in hundreds of children in this country each year.
Sadly, 60-70 percent of adults...
Acute myelogenous leukemia (AML) is one of the most common types of leukemia—a cancer of the bone marrow and blood—in adults, affecting about 13,300 women and men in the United States annually. The disease is also diagnosed in hundreds of children in this country each year.
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Starting with a discovery in zebrafish in 2007, Harvard Stem Cell Institute (HSCI) researchers have published initial results of a Phase Ib human clinical trial of a therapeutic that has the potential to improve the success of blood stem cell transplantation. This milestone, just nine short years after Harvard’s major commitment to stem cell biology, once again demonstrates the ability of HSCI investigators to carry a discovery from the lab bench to the clinic—fulfilling the promise on which the Institute was founded.... 
Using a difficult laboratory technique, HSCI physician-researchers have isolated genetically healthy stem cells from patients with Pearson Marrow Pancreas Syndrome (PS), a generally fatal infant blood disorder with less than a hundred reported cases worldwide. Children with PS experience a range of symptoms, most notably: anemia,...