Blood Diseases

Harvard-led researchers offer potential new treatments for subtype of acute myeloid leukemia

December 23, 2013

An international team of researchers working in the Boston and Singapore labs of Harvard Stem Cell Institute (HSCI) Blood Program leader Daniel Tenen, MD, recently identified new candidates for the treatment of an acute myeloid leukemia (AML) subtype caused by mutations of CEBPA, a tumor suppressor. The findings were published in two separate studies:... Read more about Harvard-led researchers offer potential new treatments for subtype of acute myeloid leukemia

“Good” cells can go “bad” in a “bad neighborhood"

March 22, 2010

The general theory of cancer development holds that malignancies occur because of the presence of certain genetic elements within the affected cells.

But a new study by Harvard researchers at Massachusetts General Hospital (MGH) indicates that “good” cells can become cancerous because of exposure to a “bad” environment within the body — similarly to the way a “good boy” may turn to crime when exposed to the pressures of life in a crime-ridden neighborhood.

In their paper in today’s edition of the journal Nature, David T. Scadden and colleagues report that normal blood stem...

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