Bioengineering

Harvard scientists report on novel method for extending the life of implantable devices in situ

April 13, 2016

New approach offers promise for long-term efficacy

by Kelly Lawman, Beth Israel Deaconess Medical Center 

Blood-contacting implantable medical devices, such as stents, heart valves, ventricular assist devices, and extracorporeal support systems, as well as vascular grafts and access catheters, are used worldwide to improve patients’ lives. However, these devices are prone to failure due to the body’s responses at the blood-material interface; clots can form and inflammatory reactions can prevent the device from performing as indicated....

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Bioengineering a better quality of life for recipients of hand transplants

August 19, 2014

Researchers experiment with single shot that slows rejection

A drug-secreting gel that holds back the immune system—developed to help treat diseases such as brain cancer, ulcerative colitis, and arthritis—has now been shown to slow hand transplant rejection, in rats, when delivered through a single shot. The success may yield a new...

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