Itoh Y, Poulopoulos A, Macklis JD. Unfolding the Folding Problem of the Cerebral Cortex: Movin' and Groovin'. Dev Cell. 2017;41 (4) :332-334.Abstract
The development of reproducible folding in the gyrencephalic cerebral cortex is a topic of great interest to neuroscientists. In a recent paper in Cell, del Toro et al. (2017) show that changing the adhesive properties of neurons in the normally lissencephalic mouse cortex leads to the formation of stereotyped folding.