Liao Laboratory

Liao Laboratory
Harvard Stem Cell Institute
Center for Regenerative Medicine
Department of Surgery, Division of Plastic and Reconstructive Surgery
Harvard Medical School
Massachusetts General Hospital

Job Title:  Post-doctoral fellow.  Position is currently recruiting.  Minimum of 2-year commitment is required.

Job Description
The Liao Laboratory at the Center for Regenerative Medicine at Massachusetts General Hospital in affiliation with the Division of Plastic Surgery and the Harvard Stem Cell Institute is seeking a highly motivated research fellow interested in craniofacial developmental biology and genetics. We are diversifying our capabilities and want to utilize the best model to address different questions in craniofacial biology.  Toward that end, we are specifically interested in recruiting post-doctoral fellow with experience in iPS and mouse models to complement our current work using the zebrafish model.  The laboratory has innovated application of the zebrafish model toward the study of human craniofacial anomalies, contributing recent papers on zebrafish cleft models and its application in functional genomics to investigate the function of human genes associated with craniofacial malformations.

The fellow will join a collaborative group of scientists who study the basic and translational biology of facial morphogenesis, cranial neural crest specification and development. In this instance, the fellow’s work will have a direct bearing on discovery of drugs to mitigate malformation phenotypes and functional genomics of human candidate genes implicated in orofacial clefts. We are also inherently interested in the basic biology of neural crest cell specification, migration, differentiation and potential for regeneration. We integrate the approaches of classical developmental and modern stem cell biology and use these to explore human tissue regeneration and disease. Specific experience and expertise in mouse models, mouse genetics is strongly desired. We apply the latest technology in zebrafish genetics with routine use of CRISPR, iPS, cell transplants, FACS, live confocal labeling and imaging, transgenics, chemical screening, and many other experimental approaches. Our laboratory has a dedicated zebrafish facility outfitted with the latest imaging, injection and cell manipulation instruments. Researchers work in open format laboratory space that foster interactions with other stellar researchers working in the Center, with ample opportunities to participate in scientific seminars and professional development.

Job Requirements
The candidate should have PhD or an MD/PhD in a relevant field or equivalent training. A strong foundation in cell, developmental, or cancer biology with strong skills in genetics and molecular biology are necessary, including a foundation in the genetic modulation of a model organism. Prior experience working in mouse genetics or with iPS models is strongly desired. An ancillary knowledge of genomics or systems biology is welcome. Outstanding oral and written communication skills are required.

Please email your CV, statement of interest and career goals, and names and contact information of at least three references to Eric Liao.

Employing Department and Institution: Center for Regenerative Medicine, Massachusetts General Hospital.


See also: Job Opportunity