My laboratory studies how atherosclerosis—narrowing and hardening of the arteries—occurs. Atherosclerosis leads to abnormalities in blood vessels and...
The mission of the Humphreys Lab is to understand the cellular and molecular mechanisms of kidney injury and repair and to translate this knowledge into new therapeutic strategies to treat patients suffering from kidney disease.... Read more about Benjamin Humphreys, MD, PhD
The primary interest of our laboratory is to understand the cellular and molecular regulatory mechanisms leading to the establishment of the mammalian kidney using the mouse as a model system.... Read more about Akio Kobayashi, PhD
The muscular dystrophies are progressive disorders of striated muscle leading to breakdown of muscle integrity. Underlying this clinical presentation...
Brigham and Women's Hospital Dana-Farber Cancer Institute Harvard Medical School
Our laboratory is interested in how immune responses in skin are initiated, and how T cell mediated memory responses occur in skin, and in particular a newly described population of antigen experienced T cells known as Resident Memory T Cell (TRM).... Read more about Thomas S. Kupper, MD
Our group is working on cancer genetics, using the zebrafish genetic system to clarify developmental pathways subverted in human leukemias and solid...
The Mulligan laboratory continues to be interested in the development of methods for the introduction of genes into mammalian cells, and the application of those methods in a numbers of areas of biology and medicine.... Read more about Richard C. Mulligan, PhD
Harvard Department of Stem Cell and Regenerative Biology Brigham and Women's Hospital The Broad Institute
Our goal is to understand how naturally occurring human genetic variation protects (or predisposes) some people to cardiovascular and metabolic disease—the leading cause of death in the world—and to use that information to develop therapies that can protect the entire population from disease.... Read more about Kiran Musunuru, MD, PhD, MPH
Dr. Notarangelo's research focuses of the characterization of the molecular and cellular bases of congenital immunodeficiencies as illustrated through the study of human patients and of suitable animal models.... Read more about Luigi Notarangelo, MD
Harvard School of Public Health Dana-Farber Cancer Institute
Our research group focuses on methods spanning the laboratory to the laptop that are designed to use genomic and computational approaches to reveal the underlying biology. In particular, we have been looking at patterns of gene expression in cancer with the goal of elucidating the networks and pathways that are fundamental in the development and progression of the disease.... Read more about John Quackenbush, PhD
Senior VP for Research and Development, Tesaro, Inc.
Metastatic cancers are the major reason for treatment failure in the clinic, but we lack a detailed understanding of how primary tumors metastasize, why these secondary tumors are relatively drug resistant, and what enables cancer cells to remain dormant and then cause disease relapse many years after apparently curative treatment. We are taking a multidisciplinary approach to attack these fundamental and related problems. Our major goal is to identify important cancer gene networks that are essential in human cancer progression, to guide the development and clinical use of new cancer drugs and diagnostics.... Read more about Sridhar Ramaswamy, MD
Harvard Department of Stem Cell and Regenerative Biology
Our research aims to understand the role of long intergenic non-coding RNAs (lincRNAs) in establishing the distinct epigenetic states of adult and embryonic cells and their misregulation in diseases such as cancer.... Read more about John Rinn, PhD
Michael J. Sandel is the Anne T. and Robert M. Bass Professor of Government at Harvard University, where he has taught political philosophy since 1980....
Massachusetts General Hospital Harvard Medical School
As a surgeon-scientist in the field of Pediatric Surgery and Transplantation Surgery, my major areas of investigation and interest began with two specific diseases that are highly lethal in children; namely congenital diaphragmatic hernia and congenital biliary atresia.... Read more about Joseph Vacanti, MD