Ten years ago, scientists announced the end of the Human Genome Project, the international attempt to learn which combination of four nucleotides—adenine, thymine, cytosine, and guanine—is unique to homo sapien DNA. This biological alphabet helped...
Read more about Mapping the epigenome
New data showing human embryonic stem cell gene expression and epigenetic activity (e.g., tagging DNA to silence specific genes) reveals that stem cells prepare early to differentiate into their next form. The research, led by HSCI Principal Faculty member...
Harvard Stem Cell Institute (HSCI) researchers have found a link between male infertility and a mutation in a gene critical for sperm production. If the gene, Elongator Protein 1/Inhibitor of KappaB Kinase-associated Protein (Elp1/IKAP), is turned off, male germ cells – which give rise to sperm – encounter...
Scientists may be one step closer to being able to generate any type of cells and tissues from a patient’s own cells, according to the results of a new study by Harvard stem cell researchers at