Above, human brown fat progenitor cells express the calorie-burning, UCP1 proteins (green) as the cell differentiates. (Tseng Laboratory, Joslin Diabetes Center) 

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Harvard researchers have created a system using human stem cells to screen for compounds that have the potential to turn white, or “bad,” fat cells into brown, or “good,” fat cells. Pictured are human pluripotent stem cell-derived fat cells. (Photo...

Giant step toward new diabetes treatment

Harvard stem cell researchers today announced that they have made a giant leap forward in the quest to find a truly...

Harvard Stem Cell Institute (HSCI) Co-director Douglas Melton, PhD, and Evotec AG have entered into their second research collaboration to find biological pathways and signals that could be therapeutically relevant to diabetic patients.

The objective of this new collaboration, dubbed “TargetEEM” (Target Enteroendocrine Mechanisms), is to screen disease-relevant animal models for novel pathways and targets that have the potential to repair mechanisms involved in insulin resistance and abnormal...