Douglas Melton

HSCI co-director Douglas Melton and Evotec collaborate on diabetes

November 6, 2013

Harvard Stem Cell Institute (HSCI) Co-director Douglas Melton, PhD, and Evotec AG have entered into their second research collaboration to find biological pathways and signals that could be therapeutically relevant to diabetic patients.

The objective of this new collaboration, dubbed “TargetEEM” (Target Enteroendocrine Mechanisms), is to screen disease-relevant animal models for novel pathways and targets that have the potential to repair mechanisms involved in insulin resistance and abnormal...

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Two HSCI leaders ranked in Top 50 in world stem cell influencers

March 26, 2013

When the organizers of the upcoming World Regenerative Medicine Congress recently asked scientists and executives across the world in the stem cell and regenerative medicine fields to name “the most influential people in the global stem cell and cell therapy field,” two of HSCI’s leaders were in the top 11.

Doug Melton, HSCI’s Co-Director and Co-Founder, was named number five on the list of the world’s top 50 “Stem Cell Influencers.”  Melton, who is also co-chair of Harvard’s Department of Stem Cell and Regenerative Biology, was cited as “one of the driving forces behind...

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HSCI co-director Doug Melton is featured in WBUR radio’s Visionaries series

March 26, 2013

“Many scientists believe that human embryonic stem cells — basic cells that can develop into any tissue or organ in the body — hold the key to curing diseases like cancer, diabetes and Parkinson’s disease. In the latest installment of our “Visionaries” series, we take a look at the work of a man who has spent his career harnessing the power of stem cells to heal patients.” To listen to the radio broadcast, click here.

J&J’s Janssen Pharmaceuticals and Evotec form strategic diabetes alliance based on HSCI discoveries

July 11, 2012

A portfolio of small molecules and biologics has been licensed by Harvard University and the Howard Hughes Medical Institute from the laboratory of Harvard Stem Cell Institute Co-Director Doug Melton, co-chair of Harvard’s Department of Stem Cell and Regenerative Biology, to the German biotech firm Evotec and international giant Janssen Pharmaceuticals, a Johnson & Johnson company, as the central focus of a new program to pursue treatments and cures for diabetes.

“Our collaboration with Doug Melton’s laboratory has been extremely successful on multiple levels,” said Evotec...

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Stem cell lessons: Insights on SCNT in studies, commentary

October 5, 2011

Five years after Harvard researchers first received institutional permission to attempt to produce stem cell lines via somatic cell nuclear transfer (SCNT), a young scientist who worked in the Harvard program as a postdoctoral fellow has succeeded in using the process — known as therapeutic cloning — to produce a stem cell line containing the genes of a patient with type 1 diabetes.... Read more about Stem cell lessons: Insights on SCNT in studies, commentary