Nervous System Diseases Program

Reinventing painkillers

November 5, 2018

Clifford Woolf wants to reboot drug discovery to find a new way to treat pain: effectively and responsibly.

  • Woolf’s goal is to stop the opioid crisis by rejecting the conventional approach to drug discovery and developing painkillers that do not harm people or communities. 
  • He is using stem cells to create models of pain, outside the body and in a dish, that can be used to screen for drugs swiftly and on a large scale.
  • The new approach requires ‘all hands’: expertise, equipment, and collaboration in stem...
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NIH Makes $8.5 Million Investment in Promising Projects

October 20, 2017

HSCI Faculty ‘extraordinary’ innovation recognized by the NIH

HSCI Principal Faculty members Jeffrey Macklis, Alex Schier and Brian Wainger were recently recognized ‘for exceptional creativity’ by the NIH’s High-Risk, High-Reward Research program. Jeff and Alex each received the NIH Director’s Pioneer Award which challenges investigators at all career levels to pursue new research directions and develop groundbreaking, high-impact approaches to a broad area of biomedical or behavioral science.  Brian was bestowed the...

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