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HSCI scientist awarded grant to develop gene therapy for HIV

September 7, 2020

HSCI co-director David Scadden is part of a multi-institutional, cross-disciplinary team that has been awarded a $14.6 million grant from the National Institutes of Health. The team is using gene and cell therapy approaches to develop a potential cure for HIV.

The researchers will combine gene editing against HIV with technologies for safer and more effective blood stem cell transplants. Such transplants, also known as bone marrow transplants, are currently used for severe blood cancers. They renew a patient’s immune system, which can be damaged by cancer therapies, by...

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Assassinating cancer

November 1, 2018

Mario Suva and Ramesh Shivdasani are tackling some of the toughest, meanest cancers to clear a path to better treatments.

  • Suva and Shivdasani are using every approach in their arsenal to figure out what makes cancer cells arise from healthy tissue.
  • Armed with enough new knowledge about how cancer arises, they want to take truer aim at cancer cells, the cancer cell lineage, and factors that make cells go awry.
  • Their new approach to cancer management would combine gene and cell therapies to kill the cancer...
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