ALS

Kevin C. Eggan, PhD

Kevin C. Eggan, PhD

Harvard University Department of Stem Cell and Regenerative Biology
Howard Hughes Medical Institute

Kevin Eggan, Ph.D. Professor in the Department of Stem Cell and Regenerative Biology, Harvard University.

Jeffrey D. Macklis, MD

Jeffrey D. Macklis, MD

Harvard University Department of Stem Cell and Regenerative Biology

Our laboratory is directed toward both 1) understanding the molecular controls over neuron sub-type specification and development in the cerebral cortex, and 2) applying developmental controls toward brain and spinal cord repair—specifically, the cellular repair of complex cerebral cortex and cortical output circuitry (in particular, cortico-spinal motor neuron (CSMN) circuitry that degenerates in ALS and other “upper motor neuron” degenerative diseases, and whose injury is centrally involved in loss of motor function in spinal cord injury).

Lee L. Rubin, PhD

Lee L. Rubin, PhD

Harvard University Department of Stem Cell and Regenerative Biology

Dr. Rubin received his PhD in Neuroscience from The Rockefeller University and completed postdoctoral fellowships in Pharmacology from Harvard Medical School and in Neurobiology from Stanford University School of Medicine. He has worked both in academia and in industry.

Brian J. Wainger, MD, PhD

Brian J. Wainger, MD, PhD

Massachusetts General Hospital
Harvard Medical School

Brian Wainger’s lab fuses electrophysiology and stem cell biology to explore how abnormal neuronal physiology contributes to diseases of the motor and …