ALS

Kevin C. Eggan, PhD

Kevin C. Eggan, PhD

Harvard University Department of Stem Cell and Regenerative Biology
Howard Hughes Medical Institute

As a young investigator in the burgeoning field of stem cell biology, Dr. Eggan has garnered international recognition for his seminal work and a number of high profile awards for his creativity and productivity, including the MacArthur Foundation “Genius Grant” in 2006. His current research focuses on applying the knowledge gained in stem cell biology to studying the mechanisms underlying amyotrophic lateral sclerosis (ALS) and discovering new therapeutic targets.

Jeffrey D. Macklis, MD

Jeffrey D. Macklis, MD

Harvard University Department of Stem Cell and Regenerative Biology

Our laboratory is directed toward both 1) understanding the molecular controls over neuron sub-type specification and development in the cerebral cortex, and 2) applying developmental controls toward brain and spinal cord repair—specifically, the cellular repair of complex cerebral cortex and cortical output circuitry (in particular, cortico-spinal motor neuron (CSMN) circuitry that degenerates in ALS and other “upper motor neuron” degenerative diseases, and whose injury is centrally involved in loss of motor function in spinal cord injury).

Lee L. Rubin, PhD

Lee L. Rubin, PhD

Harvard University Department of Stem Cell and Regenerative Biology

Dr. Rubin received his PhD in Neuroscience from The Rockefeller University and completed postdoctoral fellowships in Pharmacology from Harvard Medical School and in Neurobiology from Stanford University School of Medicine. He has worked both in academia and in industry.