Massachusetts General Hospital
Job Title: Post-doctoral fellow. Position is currently recruiting. 2-year commitment is required.
The Liao Laboratory at the Center for Regenerative Medicine at Massachusetts General Hospital in affiliation with the Division of Plastic Surgery and the Harvard Stem Cell Institute is seeking a highly motivated research fellow interested in craniofacial developmental biology and genetics. The laboratory has innovated application of the zebrafish model toward the study of human craniofacial anomalies, contributing recent papers on zebrafish cleft models and its application in functional genomics to investigate the function of human genes associated with craniofacial malformations.
The fellow will join a collaborative group of scientists who study the basic and translational biology of facial morphogenesis, cranial neural crest specification and development. In this instance, the fellow’s work will have a direct bearing on discovery of drugs to mitigate malformation phenotypes and functional genomics of human candidate genes implicated in orofacial clefts. We are also inherently interested in the basic biology of neural crest cell specification, migration, differentiation and potential for regeneration. We integrate the approaches of classical developmental and modern stem cell biology and use these to explore human tissue regeneration and disease. We primarily work with the zebrafish model with collaborators in human and mouse genetics. We apply the latest technology in zebrafish genetics with routine use of CRISPR, morpholinos, cell transplants, FACS, live confocal labeling and imaging, transgenics, chemical screening, and many other experimental approaches. Our laboratory has a dedicated zebrafish facility outfitted with the latest imaging, injection and cell manipulation instruments. Researchers work in open format laboratory space that foster interactions with other stellar researchers working in the Center, with ample opportunities to participate in scientific seminars and professional development.
The candidate should have PhD or an MD/PhD in a relevant field or equivalent training. A strong foundation in cell, developmental, or cancer biology with strong skills in genetics and molecular biology are necessary, including a foundation in the genetic modulation of a model organism. Prior experience working in zebrafish genetics is strongly desired but not a requirement. An ancillary knowledge of genomics or systems biology is welcome. Knowledge of human and clinical genetics is unnecessary, as it will be acquired rapidly within the laboratory environment. Outstanding oral and written communication skills are required.
Please email your CV, statement of interest and career goals, and names and contact information of at least three references to Eric Liao.
Employing Department and Institution: Center for Regenerative Medicine, Massachusetts General Hospital.