We are looking for an exceptional Postdoctoral Associate to join Dr. Lindy Barrett's laboratory in the Stem Cell Program at the Stanley Center for Psychiatric Research at the Broad Institute, in collaboration with the Department of Stem Cell and Regenerative Biology at Harvard University.
Recent advances in human pluripotent stem cell (hPSC) biology and in vitro differentiation now allow for the generation of multiple human brain cell types in a dish. However, as with most in vitroderived cell types, human neurons remain relatively immature, more closely resembling embryonic as opposed to adult brain cells. This poses major challenges for mechanistic studies as well as disease modeling and therapeutic discovery. We are looking for a highly motivated Postdoctoral Associate to work on a funded project investigating mechanisms of synaptogenesis using in vitroderived human cortical neurons. In collaboration with Dr. Lee Rubin's laboratory, the candidate will identify pathways that modulate synapse formation using a small-scale screening approach, and perform in depth molecular and functional analyses of putative hits to understand how they impact neuronal development. The ideal candidate will be detail oriented, creative and comfortable working both independently as well as in a highly collaborative research environment. Research activities will take place at both the Broad Institute and Harvard University.
-Actively participate at cross-institutional seminars and meetings at Harvard University and the Broad Institute to discuss project plans and present data
-Willingness and drive to lead project development.
-Normal working conditions
EOE / Minorities / Females / Protected Veterans / Disabilities