Harvard Department of Stem Cell and Regenerative Biology
During embryonic development, neural progenitors undergo precise differentiation to generate the amazing variety of neuronal types that ultimately populate the mature brain. While some of the basic mechanisms that control general aspects of progenitor specification into neurons have been defined, the genetic programs that control the differentiation of distinct types of neurons in the brain are still largely unknown.
Massachusetts General Hospital
Harvard Medical School
My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through in vitro and modeling studies, with the ultimate goal of improving diagnosis, management and treatment.