Gastrointestinal Disease

Kara McKinley named Packard Fellow for Science and Engineering

October 18, 2022

 

Kara McKinley, PhD, principal faculty at HSCI, has been named one of the 2022 class of Packard Fellows for Science and Engineering. McKinley and 19 other innovative early-career scientists and engineers will each receive $875,000 over five years to pursue their research.

The Packard Fellowships for Science and Engineering are designed to encourage innovative, blue-sky thinking by providing maximum flexibility and support to...

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Gut-brain connection in autism

January 7, 2022

Harvard and MIT researchers identify possible mechanism linking autism and intestinal inflammation

Many people with autism spectrum disorders also experience unusual gastrointestinal inflammation, but thus far scientists have not established whether and how those conditions might be linked.

Now, Harvard Stem Cell Institute (HSCI) researchers at Harvard Medical School, along with MIT researchers, may have found the missing link: infections during pregnancy can lead to high levels of the inflammatory signaling molecule interleukin-17a (...

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Harald Ott and team from MGH creates functional, stem cell-derived small bowel segments

October 10, 2017

Press release of the Massachusetts General Hospital

Using human induced pluripotent stem cells (iPSCs), a Massachusetts General Hospital (MGH) research team has bioengineered functional small intestine segments that, when implanted into rats, were capable of deliver nutrients into the bloodstream. The investigators describe their accomplishment in the online journal Nature Communications.

“In this study we have been able to bridge the gap between differentiation of single cells – driving stem cells to become a specific cell type – and the...

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