Kidney Diseases Program

HSCI scientists recognized for “High-Risk, High-Reward” research

October 3, 2019

Two HSCI researchers will receive the National Institutes of Health (NIH) Director's New Innovator Award. Jason Buenrostro, Ph.D. and Ryuji Morizane, M.D., Ph.D. have been recognized for their highly innovative biomedical research that has transformative potential.

“Each year, I look forward to seeing the creative approaches these researchers take to solve tough problems in biomedical and behavioral research,” said NIH Director Francis S. Collins in the award...

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Kidney injury molecule linked to chronic kidney disease

October 2, 2013

More than 15 years after the discovery of kidney injury molecule-1 (KIM-1) by Joseph Bonventre, MD, PhD, researchers in the HSCI Kidney Disease Program—of which Bonventre is a member—have found that the molecule promotes the scar tissue formation typically associated with chronic kidney disease, which affects approximately 9-10 percent of the world’s population. The finding was made in mice.... Read more about Kidney injury molecule linked to chronic kidney disease

Patient stem cells offer insight into origins of polycystic kidney disease

September 28, 2013

Harvard Stem Cell Institute (HSCI) scientists have identified a new therapeutic approach for treating polycystic kidney disease (PKD), one of the most common life threatening, inherited diseases in humans, affecting more than 1 in 500 individuals. Patients with the disease experience an abnormal proliferation of kidney cells that ultimately results in cysts and a decline in organ function leading to kidney failure.... Read more about Patient stem cells offer insight into origins of polycystic kidney disease