Date:
Location:
Boston Single-Cell Network Seminar
Guest speakers:
Paul Blainey, PhD
Core Member, Broad Institute
Assistant Professor, Biological Engineering, MIT
and
Liyi (Lily) Xu
Graduate Student, Blainey Lab
Abstract:
The incredible biological resolution of single-cell sequencing has been clearly demonstrated in recent studies. By contrast, the accuracy and throughput of single-cell sequencing require improvement to meet the needs of many applications. Examples include analysis of rare cells in mixed populations and highly accurate determination of genotypes at the single-cell level. We will present a new approach for high-throughput whole-genome amplification of single cells and an engineered microfluidic system for sequencing library construction that exhibits performance and throughput advantages for single cell and standard sample types.
Faculty organizers: Peter Kharchenko and Lev Silberstein.
Food and beverage will be provided at the meeting.