With a series of rodent models Dr. Bonner-Weir has provided compelling evidence that adult pancreatic beta-cell mass increases in response to a metabolic need and have been examining the mechanisms of this postnatal pancreatic growth.
Harvard Department of Stem Cell and Regenerative Biology Brigham and Women's Hospital Harvard Medical School
The Lee Laboratory uses biotechnologies to discover and design new approaches to cardiovascular and metabolic diseases. We work at this interface using a broad variety of techniques in genomics, stem cell biology, and molecular biology.
One of the most important goals of diabetes research is to find sources of new beta cells (the islet cells in the pancreas that produce insulin) and to successfully transplant these cells into the pancreas.